Published: 17 April, 2019 | Volume 2 - Issue 1 | Pages: 027-050
Figure 2:
The concept of Polycythemia Vera Study Goup (PVSG) on the overlap myeloproliferative disorders (MPD) essential thrombocythemia (ET), polycythemia vera (PV), agnogenic myeloid metaplasia (AMM) and chronic myeloid leukemia (CML) was based on the 1951 Dameshek concept that the overlap MPD may be due to one hypothetical stimulans, which in retrospect appeared to be incorrect. The unifying concept of Dameshek in 1951 on the chronic myeloproliferative disorders (MPDs) PV ET AMM and CML has been broken up by the 1975 PVSG criteria by Michiels in 1987 and Georgii in 1990 into Ph-positive essential thrombocythemia (ET) and CML complicated by myelofibrosis (MF) and the Ph-negative MPDs ET, PV and MF either positive or negative for the acquired JAK2V617F mutation.
Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001004 Cite this Article Read Full Article PDF
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