Figure 4

Primary myelofibrosis is not primary anymore since the discovery of MPL515 and CALR mutations as driver causes of mono-linear megakaryocytic and dual megakaryocytic granulocytic myeloproliferation and secondary myelofibrosis

Jan Jacques Michiels* and Hendrik De Raeve

Published: 15 April, 2019 | Volume 2 - Issue 1 | Pages: 018-026

ijbmr-aid1003-g004

Figure 4:

Bone marrow biopsy showing a normocellular bone marrow with loose and dense clusters of immature large to giant megakaryocytes with hypo/hyper-lobulated hyperchromatic cloudy (bulbous) nuclei in CALR mutated ET at platelet counts around 1000x109/L and no increase of reticulin fibers grade 0/1. Source Michiels & De Raeve.

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001003 Cite this Article Read Full Article PDF

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