Figure 6

Primary myelofibrosis is not primary anymore since the discovery of MPL515 and CALR mutations as driver causes of mono-linear megakaryocytic and dual megakaryocytic granulocytic myeloproliferation and secondary myelofibrosis

Jan Jacques Michiels* and Hendrik De Raeve

Published: 15 April, 2019 | Volume 2 - Issue 1 | Pages: 018-026

ijbmr-aid1003-g006

Figure 6:

Bone marrow biopsy showing a hypercellular bone marrow (80%) due to primary megakaryocytic and granulocytic myeloproliferation (PMGM) with relative reduction of erythropoiesis and the presence of dense clustered immature megakaryocytes with hyperchromatic hypo/hyper-lobulated bulbous cloudy nuclei and slight increase og reticuline fibers grade 1 / 2 in CALR mutated thrombocythemia with moderate asymptomatic splenomegaly in the studies of Michiels & De Raeve 2018 [11,14-16].
Conclusion

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001003 Cite this Article Read Full Article PDF

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