Figure 9

European Clinical Laboratory, Molecular and Pathological (ECMP) criteria for prefibrotic JAK2V617F-Thrombocythemia and Polycythemia Vera versus MPL515- and CALR-Thrombocythemia and Myelofibrosis: From Dameshek to Michiels 1950-2018

Jan Jacques Michiels*, Zwi Berneman, Wilfried Schroyens, Fibo W J ten Kate, King Lam and Hendrik De Raeve

Published: 01 March, 2019 | Volume 2 - Issue 1 | Pages: 001-017


Figure 9:

Third ET entity presenting with JAK2 wild type prefibrotic (right panel) primary megakaryocytic and granulocytic myeloproliferation (PMGM, left and middle), which is characterized by a hypercellular bone marrow due to dual myeloproliferation of granulopoiesis and dense clustered enlarged immature dysmorphic megakaryocytes (left and middle panels) with bulky (bulbous) hyperchromatic nuclei (arrows), which are never seen in JAK2 wild type MPL515 mutated ET and also not in the prefibrotic JAK2V617F mutated ET, prodromal PV, EMGM and trilinear PV entities.

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001002 Cite this Article Read Full Article PDF

More Images

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More